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pentobarbital will reduce the level or outcome of quinine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unfamiliar.pentobarbital decreases amounts of elvitegravir/cobicistat/emtricitabine/tenofovir DF by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. May well bring on loss of virologic rea